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Junk DNA: A Journey Through the Dark Matter of the Genome

Junk DNA: A Journey Through the Dark Matter of the Genome
  

From the author of The Epigenetics Revolution ( A book that would have had Darwin swooning. --Guardian) comes a lucid and engaging report from the cutting edge of genomic biology.

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Quick Reference

ISBN 9780231170840
Barcode 9780231170840
Published 15 March 2015 by Columbia University Press
Format Hardback
Alternate Format(s) View All (5 other possible title(s) available)
Language English (translated from: English)
Author(s) By Carey, Nessa
Availability Internationally sourced on backorder; allow 4-8 weeks

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Full details for this title

ISBN-13 9780231170840
ISBN-10 023117084X
Stock Available
Status Internationally sourced on backorder; allow 4-8 weeks
Publisher Columbia University Press
Imprint Columbia University Press
Publication Date 15 March 2015
International Publication Date 14 April 2015
Publication Country United States United States
Format Hardback
Language English
Translated from English
Author(s) By Carey, Nessa
Category Award Winning
Popular Science
Evolution
DNA
Cellular Biology
Biotechnology
Number of Pages 360
Dimensions Width: 152mm
Height: 229mm
Spine: 30mm
Weight 624g
Interest Age General Audience
Reading Age General Audience
Library of Congress Genomics, Human genome, Eukaryotic cells, Gene therapy, Recombinant DNA
NBS Text Popular Science
ONIX Text Professional and scholarly
Dewey Code 572.86
Catalogue Code Not specified

Description of this Book

For decades after identifying the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98% of the human genome were dismissed as junk, sequences that serve no purpose. Yet recently researchers have discovered variations and modulations in this junk DNA that underwrite a number of intractable diseases. This knowledge has led to innovative research and treatment approaches that may finally control these conditions. Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes. Its function has forced scientists to revisit the very meaning of the word gene and has engendered a bitter battle over whether or not this genomic nonsense is the source of human biological complexity. Drawing on her experience with leading investigators in Europe and North America, Nessa Carey provides a clear and compelling introduction to junk DNA and its critical involvement in phenomena as diverse as genetic diseases, viral infections, sex determination in mammals, disease treatments, and evolution. We are only now unlocking the secrets of junk DNA, and Carey's book is an indispensable resource for navigating the codes and controversies of this fast-growing and hotly disputed field.

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Awards, Reviews & Star Ratings

Awards Commended for One of The Independent's Best Science Books 2015
NZ Review Engaging, informative, and humorous, Dr. Carey's appealing book will be of interest to many readers. -- Sharon Y.R. Dent, Ph.D., University of Texas MD Anderson Cancer Center

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Author's Bio

Nessa Carey is a visiting professor at Imperial College, London. She earned her Ph.D. in virology from the University of Edinburgh. Having worked in the biotech and pharmaceutical industries for more than a decade, she maintains strong relationships with leading researchers in Europe and across the United States, at such institutions as the Harvard Medical School, the University of Pennsylvania, the Wistar Institute, the MD Anderson Cancer Center, and the University of Southern California. Carey is also the author of The Epigenetics Revolution: How Modern Biology Is Rewriting Our Understanding of Genetics, Disease, and Inheritance.

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