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              Books by Adam C. Berger

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              The Value of Genetic and Genomic Technologies: Workshop Summary

              The Value of Genetic and Genomic Technologies: Workshop Summary (Trade Paperback / Paperback)

              By Roundtable on Translating Genomic-Based Research for Health; on Health Sciences Policy, Board; Institute of Medicine; Edited by Berger, Adam C.; Wizemann, Theresa

              • RRP: $45.99
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              Knowing one's genetic disposition to a variety of diseases, including common chronic diseases, can benefit both the individual and society at large. The IOM's Roundtable on Translating Genomic-Based Research for Health held a workshop on March 22, 2010, to bring together diverse ...perspectives on the value of genetic testing, and to discuss its use in clinical practice --home page.
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              ISBN 9780309157711
              Released NZ 15 Nov 2010
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              Genome-Based Diagnostics: Demonstrating Clinical Utility in Oncology: Workshop Summary

              Genome-Based Diagnostics: Demonstrating Clinical Utility in Oncology: Workshop Summary (Trade Paperback / Paperback)

              By Roundtable on Translating Genomic-Based Research for Health; on Health Sciences Policy, Board; Institute of Medicine; for Medical Technology Policy, Center; Edited by Berger, Adam C.

              • RRP: $59.99
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              Presents the summary of a workshop convened in May 2012 by the Roundtable on Translating Genomic-Based Research for Health and the Center for Medical Technology Policy of the Institute of Medicine to foster the identified need for further sustained dialogue between stakeholders r...egarding the clinical utility of molecular diagnostics.
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              ISBN 9780309269599
              Released NZ 15 May 2014
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              Genome-Based Diagnostics: Clarifying Pathways to Clinical Use: Workshop Summary

              Genome-Based Diagnostics: Clarifying Pathways to Clinical Use: Workshop Summary (Trade Paperback / Paperback)

              By Roundtable on Translating Genomic-Based Research for Health; on Health Sciences Policy, Board; Institute of Medicine; Edited by Olson, Steve; Berger, Adam C.

              • RRP: $53.99
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              The sequencing of the human genome and the identification of associations between specific genetic variants and diseases have led to an explosion of genomic-based diagnostic tests. These tests have the potential to direct therapeutic interventions, predict risk or onset of diseas...e, or detect residual disease. As research progresses and an increasing number of associations are found, further tests will be developed that can aid in providing personalized treatment options for patients. However, the adoption of genomic diagnostic tests by health care providers has been limited due to a lack of evidence regarding the clinical utility of many tests. Health funders and practitioners lack the data necessary to distinguish which tests can improve practice or the clinical settings in which tests will provide the greatest value. The Roundtable on Translating Genomic-Based Research for Health held a workshop in November 2010 to determine what evidence is needed and how it is viewed by different stakeholders in order to develop genomic diagnostic tests of clinical value. Genome-Based Diagnostics summarizes the presentations and discussions that took place throughout the workshop. Two presentations, in particular, sparked extensive discussion. One presentation proposed that all genomic diagnostic tests be reviewed and approved by the Food and Drug Administration. The other observed that venture capitalists are no longer investing substantially in the development of genomic diagnostic tests because of a lack of clarity surrounding regulatory and reimbursement pathways. Both presentations suggested the need for major changes in the systems used to develop, regulate, and reimburse genomic diagnostic tests. The report also presents the perspectives of different stakeholders in the development of genomic diagnostic tests. Each stakeholder group has a different set of needs and issues of importance, yet commonalities among them are apparent, such as the need to put patients and health
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              ISBN 9780309253949
              Released NZ 15 Dec 2012
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              The Economics of Genomic Medicine: Workshop Summary

              The Economics of Genomic Medicine: Workshop Summary (Trade Paperback / Paperback)

              By Roundtable on Translating Genomic-Based Research for Health; on Health Sciences Policy, Board; Institute of Medicine; Edited by Berger, Adam C.; Olson, Steve

              • RRP: $65.00
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              The Economics of Genomic Medicine: Workshop Summary

              ISBN 9780309269681
              Released NZ 15 Jul 2013
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              Generating Evidence for Genomic Diagnostic Test Development: Workshop Summary

              Generating Evidence for Genomic Diagnostic Test Development: Workshop Summary (Trade Paperback / Paperback)

              By Roundtable on Translating Genomic-Based Research for Health; on Health Sciences Policy, Board; Institute of Medicine; Edited by Berger, Adam C.; Wizemann, Theresa

              • RRP: $45.99
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              Ten years after the sequencing of the human genome, scientists have developed genetic tests that can predict a person's response to certain drugs, estimate the risk of developing Alzheimer's disease, and make other predictions based on known links between genes and diseases. Howe...ver, genetic tests have yet to become a routine part of medical care, in part because there is not enough evidence to show they help improve patients' health.The Institute of Medicine (IOM) held a workshop to explore how researchers can gather better evidence more efficiently on the clinical utility of genetic tests. Generating Evidence for Genomic Diagnostic Test Development compares the evidence that is required for decisions regarding clearance, use, and reimbursement, to the evidence that is currently generated. The report also addresses innovative and efficient ways to generate high-quality evidence, as well as barriers to generating this evidence. Generating Evidence for Genomic Diagnostic Test Development contains information that will be of great value to regulators and policymakers, payers, health-care providers, researchers, funders, and evidence-based review groups. --Publisher's description.
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              ISBN 9780309211048
              Released NZ 15 Jun 2011
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              Genome-Based Therapeutics: Targeted Drug Discovery and Development: Workshop Summary

              Genome-Based Therapeutics: Targeted Drug Discovery and Development: Workshop Summary (Trade Paperback / Paperback)

              By Roundtable on Translating Genomic-Based Research for Health; on Health Sciences Policy, Board; Institute of Medicine; Edited by Berger, Adam C.; Olson, Steve

              • RRP: $55.99
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              The number of new drug approvals has remained reasonably steady for the past 50 years at around 20 to 30 per year, while at the same time the total spending on health-related research and development has tripled since 1990. There are many suspected causes for this trend, includin...g increases in regulatory barriers, the rising costs of scientific inquiry, a decrease in research and development efficiency, the downstream effects of patient expirations on investment, and the lack of production models that have successfully incorporated new technology. Regardless, this trajectory is not economically sustainable for the businesses involved, and, in response, many companies are turning toward collaborative models of drug development, whether with other industrial firms, academia, or government. Introducing greater efficiency and knowledge into these new models and aligning incentives among participants may help to reverse the trends highlighted above, while producing more effective drugs in the process. Genome-based therapeutics explains that new technologies have the potential to open up avenues of development and to identify new drug targets to pursue. Specifically, improved validation of gene-disease associations through genomics research has the potential to revolutionize drug production and lower development costs. Genetic information has helped developers by increasing their understanding of the mechanisms of disease as well as individual patients' reactions to their medications. There is a need to identify the success factors for the various models that are being developed, whether they are industry-led, academia-led, or collaborations between the two. Genome-Based Therapeutics summarizes a workshop that was held on March 21, 2012, titled New paradigms in drug discovery: how genomic data are being used to revolutionize the drug discovery and development process. At this workshop the goal was to examine the general approaches being used to apply successes achieved so
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              ISBN 9780309260244
              Released NZ 15 Nov 2012
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              Establishing Precompetitive Collaborations to Stimulate Genomics-Driven Product Development: Workshop Summary

              Establishing Precompetitive Collaborations to Stimulate Genomics-Driven Product Development: Workshop Summary (Trade Paperback / Paperback)

              By on Health Sciences Policy, Board; Roundtable on Translating Genomic-Based Research on Health; Institute of Medicine; Edited by Berger, Adam C.; Olson, Steve

              • RRP: $33.99
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              Despite the many basic research discoveries in genetics, relatively few gene-based treatments, drugs, or preventative measures have been developed. One way to bridge this gap may be for industry, academia, and government to develop partnerships that share resources while distribu...ting risk. However, intellectual property protections and other barriers can inhibit collaborative efforts. The Institute of Medicine held a workshop on July 22, 2010, to explore these issues and develop solutions. --Publisher's description.
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              ISBN 9780309161824
              Released NZ 15 Feb 2011
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              Challenges and Opportunities in Using Residual Newborn Screening Samples for Translational Research: Workshop Summary

              Challenges and Opportunities in Using Residual Newborn Screening Samples for Translational Research: Workshop Summary (Trade Paperback / Paperback)

              By Roundtable on Translating Genomic-Based Research for Health; on Health Sciences Policy, Board; Institute of Medicine; Edited by Berger, Adam C.; Olson, Steve

              • RRP: $33.99
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              Newborn screening samples are used to test more than 4 million infants each year for life-threatening diseases that are treatable if found at birth. These specimens also represent a potentially invaluable resource for public health and biomedical research. The IOM held a workshop... to examine issues surrounding the use of residual specimens for translational research.
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              ISBN 9780309159548
              Released NZ 15 Nov 2010
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              Total 8 jump to: go