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            The Cheating Cell: How Evolution Helps Us Understand and Treat Cancer

            The Cheating Cell: How Evolution Helps Us Understand and Treat Cancer (Hardback)

            By Aktipis, Athena

            • RRP: $70.99
            • $63.89
            • Save $7.10
            • Delayed Release

            A fundamental and groundbreaking reassessment of how we view and manage cancer When we think of the forces driving cancer, we don't necessarily think of evolution. But evolution and cancer are closely linked, for the historical processes that created life also created cancer. The... Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer's evolutionary origins, researchers can come up with more effective, revolutionary treatments. Athena Aktipis goes back billions of years to explore when unicellular forms became multicellular organisms. Within these bodies of cooperating cells, cheating ones arose, overusing resources and replicating out of control, giving rise to cancer. Aktipis illustrates how evolution has paved the way for cancer's ubiquity, and why it will exist as long as multicellular life does. Even so, she argues, this doesn't mean we should give up on treating cancer-in fact evolutionary approaches offer new and promising options for the disease's treatment and prevention that aim at long-term management rather than simply eradication. Looking across species-from sponges and cacti to dogs and elephants-we are discovering new mechanisms of tumor suppression and the many ways that multicellular life-forms have evolved to keep cancer under control. By accepting that cancer is a part of our biological past, present, and future-and that we cannot win a war against evolution-treatments can become smarter, more strategic, and more humane. Unifying the latest research from biology, ecology, medicine, and social science, The Cheating Cell challenges us to rethink cancer's fundamental nature and our relationship to it.
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            ISBN 9780691163840
            Released NZ 15 Feb 2020
            Publisher Princeton University Pre
            Interest Age General Audience
            Availability
            Pre-order title, release date has been delayed
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            The DNA Guide for Adoptees: How to use genealogy and genetics to uncover your roots, connect with your biological family, and better understand your medical history.
             

            The DNA Guide for Adoptees: How to use genealogy and genetics to uncover your roots, connect with your biological family, and better understand your medical history. (Trade Paperback / Paperback)

            By Combs-Bennett, Shannon; Kirkpatrick, Brianne

            • RRP: $68.99
            • $68.99
            • In Stock US

            Welcome to The DNA Guide for Adoptees: How to use genealogy and genetics to uncover your roots, connect with your biological family, and better understand your medical history. If you are an adoptee, there's likely missing information about your past and you hope to change that. ...You've come to the right place! This book is for you if you have hope that DNA testing might open up the search for information about yourself, your origins, and your future. We've worked hard to compile the resources in this book and explain in plain English how DNA and genealogical records fit together like the pieces of a puzzle. In the chapters that follow, we've created a place for you to turn as you come face-to-face with questions about health, ancestry, biological family, and DNA. Why DNA testing, and why now? DNA testing is a game-changer for people researching family connections. Many recent advances have made it possible for adoptees to search for answers more easily than they could have done even a few years ago. Consider the following changes: At-home DNA tests have grown in number and dropped in price. Millions of people use software to build and track their family trees and share results online. Billions of vital records, legal files, and other documents are available online. Social networks and search engines make it easy to find and connect to people all over the world. Adoptees are sharing their DNA stories publicly, through television shows and other media. While advances in DNA testing are exciting and useful, there are real limitations, and we will be the first to acknowledge that DNA doesn't hold all of the answers for everyone. Nevertheless, it plays an important role for adoptees hoping to learn more about themselves and their genetics. In some cases, DNA testing has helped adoptees discover unknown medical risks, which is invaluable in situations where little or no family health history is available. You may have already started down the path of DNA testing, or it ma
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            ISBN 9781733734301
            Released NZ 26 May 2019
            Publisher R. R. Bowker
            Interest Age General Audience
            Availability
            Internationally sourced; ships 6-12 working days
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            The Lost Family: How DNA Testing Is Upending Who We Are
             

            The Lost Family: How DNA Testing Is Upending Who We Are (EPUB ebook)

            By Copeland, Libby

            A deeply reported look at the rise of home genetic testing and the seismic shock it has had on individual lives You swab your cheek or spit into a vial, then send it away to a lab somewhere. Weeks later you get a report that might tell you where your ancestors came from or if you... carry certain genetic risks. Or the report could reveal a long-buried family secret and upend your entire sense of identity. Soon a lark becomes an obsession, an incessant desire to find answers to questions at the core of your being, like "Who am I?" and "Where did I come from?" Welcome to the age of home genetic testing. In The Lost Family, journalist Libby Copeland investigates what happens when we embark on a vast social experiment with little understanding of the ramifications. Copeland explores the culture of genealogy buffs, the science of DNA, and the business of companies like Ancestry and 23andMe, all while tracing the story of one woman, her unusual results, and a relentless methodical drive for answers that becomes a thoroughly modern genetic detective story. The Lost Family delves into the many lives that have been irrevocably changed by home DNA tests-a technology that represents the end of family secrets. There are the adoptees who've used the tests to find their birth parents; donor-conceived adults who suddenly discover they have more than fifty siblings; hundreds of thousands of Americans who discover their fathers aren't biologically related to them, a phenomenon so common it is known as a "non-paternity event"; and individuals who are left to grapple with their conceptions of race and ethnicity when their true ancestral histories are discovered. Throughout these accounts, Copeland explores the impulse toward genetic essentialism and raises the question of how much our genes should get to tell us about who we are. With more than thirty million people having undergone home DNA testing, the answer to that question is more important than ever. Gripping and masterfully told,
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            ISBN 9781683358930
            Available in EPUB
            Software Read in Browser or Adobe Ebook Compatible Device
            Language en
            Released NZ 3 Mar 2020
            Publisher Abrams
            Interest Age General Audience
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            Skin Deep: Journeys in the Divisive Science of Race

            Skin Deep: Journeys in the Divisive Science of Race (Hardback)

            By Evans, Gavin

            • RRP: $42.99
            • $34.39
            • Save $8.60
            • In Stock At Publisher

            It's 2019, and eugenics is back on the agenda.

            ISBN 9781786076229
            Released NZ 5 Nov 2019
            Publisher Misc - United Book Distributor
            Interest Age General Audience
            Availability
            In stock at publisher; ships 6-12 working days
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            Hacking the Code of Life: How gene editing will rewrite our futures

            Hacking the Code of Life: How gene editing will rewrite our futures (Trade Paperback / Paperback)

            By Carey, Nessa

            • RRP: $32.99
            • $25.73
            • Save $7.26
            • In Stock At Publisher

            The cutting-edge science that will revolutionise the way we prevent disease

            ISBN 9781785784972
            Released NZ 15 Apr 2019
            Publisher Icon Books Ltd
            Interest Age General Audience
            Series Hot Science
            Availability
            In stock at publisher; ships 6-12 working days
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            Genetic Testing
              

            Genetic Testing (Hardback)

            By Boslaugh, Sarah

            • RRP: $149.99
            • $149.99
            • In Stock US

            Genetic testing has provided important clues to understanding our health, but it has also raised many ethical, legal, and medical questions and concerns. This book explores the breadth of genetic testing, its possibilities, and the controversies that surround its use --

            ISBN 9781440866500
            Released NZ 7 Jan 2020
            Publisher ABC-CLIO
            Interest Age 19+ years
            Series Health and Medical Issues Today
            Availability
            Internationally sourced; ships 6-12 working days
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            The Value of Genetic and Genomic Technologies: Workshop Summary

            The Value of Genetic and Genomic Technologies: Workshop Summary (Trade Paperback / Paperback)

            By Roundtable on Translating Genomic-Based Research for Health; on Health Sciences Policy, Board; Institute of Medicine; Edited by Berger, Adam C.; Wizemann, Theresa

            • RRP: $45.99
            • $43.69
            • Save $2.30
            • Available At Publisher

            Knowing one's genetic disposition to a variety of diseases, including common chronic diseases, can benefit both the individual and society at large. The IOM's Roundtable on Translating Genomic-Based Research for Health held a workshop on March 22, 2010, to bring together diverse ...perspectives on the value of genetic testing, and to discuss its use in clinical practice --home page.
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            ISBN 9780309157711
            Released NZ 15 Nov 2010
            Publisher FOOTPRINT BOOKS
            Interest Age General Audience
            Availability
            Showing available at publisher; usually ships 7-14 working days
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            Genome-Based Diagnostics: Demonstrating Clinical Utility in Oncology: Workshop Summary

            Genome-Based Diagnostics: Demonstrating Clinical Utility in Oncology: Workshop Summary (Trade Paperback / Paperback)

            By Roundtable on Translating Genomic-Based Research for Health; on Health Sciences Policy, Board; Institute of Medicine; for Medical Technology Policy, Center; Edited by Berger, Adam C.

            • RRP: $59.99
            • $56.99
            • Save $3.00
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            Presents the summary of a workshop convened in May 2012 by the Roundtable on Translating Genomic-Based Research for Health and the Center for Medical Technology Policy of the Institute of Medicine to foster the identified need for further sustained dialogue between stakeholders r...egarding the clinical utility of molecular diagnostics.
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            ISBN 9780309269599
            Released NZ 15 May 2014
            Publisher FOOTPRINT BOOKS
            Interest Age General Audience
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            Showing available at publisher; usually ships 7-14 working days
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            Genome-Based Diagnostics: Clarifying Pathways to Clinical Use: Workshop Summary

            Genome-Based Diagnostics: Clarifying Pathways to Clinical Use: Workshop Summary (Trade Paperback / Paperback)

            By Roundtable on Translating Genomic-Based Research for Health; on Health Sciences Policy, Board; Institute of Medicine; Edited by Olson, Steve; Berger, Adam C.

            • RRP: $53.99
            • $51.29
            • Save $2.70
            • Available At Publisher

            The sequencing of the human genome and the identification of associations between specific genetic variants and diseases have led to an explosion of genomic-based diagnostic tests. These tests have the potential to direct therapeutic interventions, predict risk or onset of diseas...e, or detect residual disease. As research progresses and an increasing number of associations are found, further tests will be developed that can aid in providing personalized treatment options for patients. However, the adoption of genomic diagnostic tests by health care providers has been limited due to a lack of evidence regarding the clinical utility of many tests. Health funders and practitioners lack the data necessary to distinguish which tests can improve practice or the clinical settings in which tests will provide the greatest value. The Roundtable on Translating Genomic-Based Research for Health held a workshop in November 2010 to determine what evidence is needed and how it is viewed by different stakeholders in order to develop genomic diagnostic tests of clinical value. Genome-Based Diagnostics summarizes the presentations and discussions that took place throughout the workshop. Two presentations, in particular, sparked extensive discussion. One presentation proposed that all genomic diagnostic tests be reviewed and approved by the Food and Drug Administration. The other observed that venture capitalists are no longer investing substantially in the development of genomic diagnostic tests because of a lack of clarity surrounding regulatory and reimbursement pathways. Both presentations suggested the need for major changes in the systems used to develop, regulate, and reimburse genomic diagnostic tests. The report also presents the perspectives of different stakeholders in the development of genomic diagnostic tests. Each stakeholder group has a different set of needs and issues of importance, yet commonalities among them are apparent, such as the need to put patients and health
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            ISBN 9780309253949
            Released NZ 15 Dec 2012
            Publisher FOOTPRINT BOOKS
            Interest Age General Audience
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            Showing available at publisher; usually ships 7-14 working days
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            Integrating Large-Scale Genomic Information into Clinical Practice: Workshop Summary

            Integrating Large-Scale Genomic Information into Clinical Practice: Workshop Summary (Trade Paperback / Paperback)

            By Roundtable on Translating Genomic-Based Research for Health; on Health Sciences Policy, Board; Institute of Medicine; Edited by Olson, Steve; Beachy, Sarah H.

            • RRP: $57.99
            • $55.09
            • Save $2.90
            • Available At Publisher

            The initial sequencing of the human genome, carried out by an international group of experts, took 13 years and $2.7 billion to complete. In the decade since that achievement, sequencing technology has evolved at such a rapid pace that today a consumer can have his or her entire ...genome sequenced by a single company in a matter of days for less than $10,000, though the addition of interpretation may extend this time frame. Given the rapid technological advances, the potential effect on the lives of patients, and the increasing use of genomic information in clinical care, it is important to address how genomics data can be integrated into the clinical setting. Genetic tests are already used to assess the risk of breast and ovarian cancers, to diagnose recessive diseases such as cystic fibrosis, to determine drug dosages based on individual patient metabolism, and to identify therapeutic options for treating lung and breast tumors, melanoma, and leukemia. With these issues in mind and considering the potential impact that genomics information can have on the prevention, diagnosis, and treatment of disease, the Roundtable on Translating Genomic-Based Research for Health hosted a workshop on July 19, 2011, to highlight and identify the challenges and opportunities in integrating large-scale genomic information into clinical practice. Integrating large-scale genomic information into clinical practice summarizes the speaker presentations and the discussions that followed them. This report focuses on several key topics, including the analysis, interpretation, and delivery of genomic information plus workforce, ethical, and legal issues.
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            ISBN 9780309220347
            Released NZ 15 Feb 2012
            Publisher FOOTPRINT BOOKS
            Interest Age General Audience
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            Showing available at publisher; usually ships 7-14 working days
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